Health

Genetically edited pig organ transplant monkey body is expected to be implanted in the human body in the future

domestic pig grazing on green grass during daytime
pig
In recent years, experts have suggested that the number of organs donated by humans is limited.

In the face of such a large supply and demand gap. It is recommend to implant animal organs into the human body.  In addition to independently cultivate transplant organs in the laboratory. Currently, eGenesis, led by Harvard University geneticist George Church. Is improving pig organs so that they can eventually be transplant to human patients.

According to the British Daily Mail reported that the pig organs will be transplanted into human patients one day in the future. The current global demand for organ donation is large, the supply is in short supply. At the same time. Pig organs and Human organs are close in size and are the best choice for human xenograft organs.

pig organs can transplant into monkeys

  The US startup eGenesis has established a partnership with the Massachusetts General Hospital to test whether pig organs can transplant into monkeys. If this experiment is successful, it may lay the foundation for human xenograft surgery to test whether pig organs can be safely transplanted into monkeys.

  Currently, researchers are using cutting-edge gene editing techniques to modify pre-transplantation organs. Thereby reducing the risk of transplant organs being physically reject by patients. And the need for patients to supply organ transplants far exceeds actual reserves.

The number of organs donate by humans is limite

  In recent years, experts have suggested that the number of organs donated by humans is limited. In the face of such a large supply and demand gap. It is recommend to implant animal organs into the human body, or to independently cultivate transplant organs in the laboratory. Currently, eGenesis, led by Harvard University geneticist George Church. Is improving pig organs so that they can eventually transplant to human patients.

brown coated monkey on branch
monkey
Pig organs can be transplanted into the monkey body

The American startup eGenesis has established a partnership with the Massachusetts General Hospital to test whether pig organs can be transplanted into the monkey body. If this experiment is successful. after that It may lay the foundation for human xenograft surgery to test whether pig organs can be safely transplanted into the monkey body.

The size of the pig’s organs is very close to that of human organs

  Transplantation of pig organs into human patients may be a good option because the size of the pig’s organs is very close to that of human organs. One of the main challenges of cross-species organ transplantation is to suppress the immune response of the recipient, otherwise the immune response will attack the donor organ. Professor Church and his colleagues are using CRISPR gene editing technology to improve the pig’s organs, making it less likely to be Rejection. In an experiment conducted at the Massachusetts General Hospital, eGenesis researchers implanted transplanted organs into monkeys and tested human health after organ implantation.

  The MIT Technical Review reports that the exact nature of the current experiment—what organs are being transplant. The types of monkeys that are being test, and how the pigs are rais. Have been keep secret so far, however, pig organs. It has not been transplant to the body of primates for the first time. Previously, researchers at the National Institutes of Health successfully implanted the pig’s heart into the sputum. And the experts succeeded in allowing the transplanted heart to survive and bounce for two years.

  What is a xenotransplantation?

  In another study in 2018, German researchers reported that several baboons implanted in the heart of the pig survived for about six months. If these experiments are finally prove to be successful, the researchers may eventually begin testing whether cross-species transplantation can be applie to humans and whether it is possible to slow the current demand for donor organs.

  In 2015, eGenesis announced that it has raised more than $38 million to support research and development. Basically, this research area has been stagnant for 15 years. Some true adherents are fully engage. However eGenesis say that our latest research project is to reintroduce organ transplants between different species. Which is believe to completely change the rules of the game.

In another study in 2018. German researchers reported that several baboons implanted in the heart of the pig survived for about six months.

  The process of transplanting a healthy heart from one animal to another is call “xenografting.” Xenografts have long been known as a potential way to cure life-threatening and life-threatening heart disease patients. As people’s life expectancy increases around the world, more and more people are waiting for death or xenotransplantation.

  If an organ transplant is unsuccessful, many chronic diseases can lead to death. According to the World Health Organization, animal-derive organs. Tissues and living cells may be perfectly integrate with human body fluids, cells, tissues or organs to form living organs and tissues. Which may become a substitute for human origin and fill human transplantation. Empty vacancies.

Natural immune response usually rejects the transplanted organ

  In addition, a statement from the World Health Organization urged member states to ensure effective national regulatory control and monitoring mechanisms prior to xenotransplantation. For patients, the natural immune response usually rejects the transplanted organ. Which is very dangerous for the patient.Maybe in the future animal organs can transplantation into the human body.

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